A green synthesis method-nitrile hydration to synthesize amide

Amide compounds which are closely related to people's clothing, food, shelter, and transportation play an important role in daily production life. Therefore, exploring improving the synthesis of amide is one topics that researchers have focused on recent years. The hydration nitriles amides environmental-friendly 100% atom economic method. Among reported nitrile catalytic systems, metal complexes attracted considerable attention due their high activity, excellent selectivity, mild reaction conditions, tunability performance at a molecular level. In this paper, we summarize progress complex catalysts understanding mechanism, provides basis for industrialization catalysts.